MS2PIP: a tool for MS/MS peak intensity prediction

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MS2PIP: a tool for MS/MS peak intensity prediction

MOTIVATION Tandem mass spectrometry provides the means to match mass spectrometry signal observations with the chemical entities that generated them. The technology produces signal spectra that contain information about the chemical dissociation pattern of a peptide that was forced to fragment using methods like collision-induced dissociation. The ability to predict these MS(2) signals and to u...

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Data and text mining MS2PIP: a tool for MS/MS peak intensity prediction

Motivation: Tandem mass spectrometry provides the means to match mass spectrometry signal observations with the chemical entities that generated them. The technology produces signal spectra that contain information about the chemical dissociation pattern of a peptide that was forced to fragment using methods like collision induced dissociation. The ability to predict these MS signals and to und...

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We present an MS(2) peak intensity prediction server that computes MS(2) charge 2+ and 3+ spectra from peptide sequences for the most common fragment ions. The server integrates the Unimod public domain post-translational modification database for modified peptides. The prediction model is an improvement of the previously published MS(2)PIP model for Orbitrap-LTQ CID spectra. Predicted MS(2) sp...

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MSPIP: a tool for MS/MS peak intensity prediction

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2013

ISSN: 1460-2059,1367-4803

DOI: 10.1093/bioinformatics/btt544